Considerations To Know About pharmaceutical APIs and their source

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Daunorubicin interacts with DNA by intercalation and inhibition of macromolecular biosynthesis. This inhibits the progression of the enzyme topoisomerase II, which relaxes supercoils in DNA for transcription.

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Epirubicin is favoured about doxorubicin, the preferred anthracycline, in a few chemotherapy regimens as it appears to result in much less Unintended effects. In 1999 epirubicin received FDA acceptance being a element of adjuvant therapy in node-optimistic patients.